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First received: March 29, 2023

Clinical Trial: Treatment of LSCD With DM

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Limbal Stem-cell Deficiency

Study Type: INTERVENTIONAL


Official Title: Treatment of Limbal Stem Cell Deficiency With Descemet's Membrane

Brief Summary: Limbal Stem Cell Deficiency (LSCD) is a blinding disease that accounts for an estimated 15-20% of corneal blindness worldwide.Current treatments are limited.Traditional corneal transplantation with penetrating keratoplasty (PKP) is ineffective in treating these patients.Without a healthy population of limbal stem cells (LSC) to regenerate the corneal epithelium, standard corneal transplants will not re-epithelialize and will rapidly scar over or melt.The limbal niche is the microenvironment surrounding the LSCs…

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