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First received: May 19, 2023

Clinical Trial: The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Parkinson Disease

Study Type: INTERVENTIONAL


Official Title: The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease

Brief Summary: Fifteen PwPD who have undergone DBS surgery and utilize the Percept system will complete a FE and VE exercise session on a stationary cycle while Off antiparkinsonian medication.Bilateral neural activity of the STN will be continuously recorded for 130 minutes (pre-, during FE or VE and post-exercise).The Movement Disorders Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS) III Motor Exam and upper extremity force-tracking task will be used to determine motor response to exercise.

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