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First received: May 25, 2023

Clinical Trial: Broccoli Extract Supplementation in Older Adults With Alcohol Use Disorder

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Alcohol Use Disorder

Study Type: INTERVENTIONAL


Official Title: Broccoli Extract Supplementation and Gastrointestinal Health in Older Adults With Active Alcohol Use and Low Diet Quality

Brief Summary: Chronic alcohol consumption leads to perturbations in gut microbiome balance (dysbiosis) and disruption of gut barrier integrity.As a result, bacteria, toxins, and metabolites can enter the blood stream and reach distant organs, triggering inflammation and oxidative stress.Through this mechanism gut leak is closely related to the onset of metabolic diseases, such as nonalcoholic fatty liver disease (NAFLD) and diabetes.Despite the prominent role of diet and alcohol in the pathogenesis of metabolic diseases, there…

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