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First received: February 20, 2023

Clinical Trial: French National MICMAF Cohort

Study Status: Completed

Recruit Status: RECRUITING

Condition: Alcoholic Liver Disease

Study Type: OBSERVATIONAL


Official Title: Study of the Evolution of the Intestinal Microbiome (Taxonomic and Functional Composition) During Alcoholic Liver Disease

Brief Summary: Excessive alcohol consumption is a major public health problem, particularly in France.It is the leading cause of cirrhosis and hepatocellular carcinoma.Among subjects with heavy alcohol consumption, the majority of patients develop fatty liver overload (steatosis), but only 10 to 35% develop acute alcoholic hepatitis (AAH) and 8 to 20% progress to cirrhosis.Steatosis is the earliest lesion, rapidly reversible after abstinence from alcohol.On the other hand, the occurrence of HAA leads to a strong progression of…

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