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First received: May 24, 2023

Clinical Trial: Ethosomal Gel Bearing Losartan 5% for Keloid Treatment

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Keloid

Study Type: INTERVENTIONAL


Official Title: The Effect of Ethosomal Gel Bearing Losartan 5% on The Patient and Observer Scar Assessment Scale Score, Degree of Erythema and Pigmentation, Surface Area, Thickness and Pliability of Human Keloids

Brief Summary: Keloid is a fibroproliferative disorder of the skin that passes through the initial trauma area.Treatment of keloids is still a challenge because the efficacy of therapy varies between studies.Standard treatment using triamcinolone acetonide injection can cause various side effects.The efficacy of topical therapy for keloids varies.Angiotensin II in human skin, when it binds to the angiotensin II receptor type 1 (AT1R), will have pro-inflammatory, pro-proliferative and pro-fibrosis effects.This mechanism plays a…

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