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First received: May 22, 2023

Clinical Trial: Prevention of Organ Dysfunction and Mortality by Monitoring the Administration of Opioids and Hypnotics in Patients at High Postoperative Risk

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Sedation and Analgesia Monitoring

Study Type: INTERVENTIONAL


Official Title: Prevention of Organ Dysfunction and Mortality by Monitoring the Administration of Opioids and Hypnotics in Patients at High Postoperative Risk: the Opti-Two Study. A Multi-center Controlled Randomized

Brief Summary: Intraoperative hypotension is a common situation.It increases postoperative morbidity and mortality, especially in patients at high postoperative risk undergoing high-risk surgery.Intraoperative hypotension is partly related to anesthesia, and mainly to the combined, dose-dependent, synergistic effect of hypnotics and opioids.Monitoring sedation and monitoring analgesia reduce intraoperative consumption of each anesthetic agent.To date, the beneficial effect of combined sedation and analgesia monitoring on the…

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