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First received: April 04, 2023

Clinical Trial: Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Study Status: Completed

Recruit Status: RECRUITING

Condition: Rheumatoid Arthritis

Study Type: INTERVENTIONAL


Official Title: A Phase 3b/4 Randomized, Double-Blind, Double Dummy, Active Comparator-Controlled Study, Comparing the Efficacy and Safety of Upadacitinib Versus Adalimumab in Subjects With Moderate to Severe Rh

Brief Summary: Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function.This study will assess how safe and effective upadacitinib is in treating RA when compared to adalimumab in adult participants with inadequate response or intolerance to one TNF-inhibitor who are on a stable dose of methotrexate (MTX).Adverse events and change in disease activity will be assessed.Upadacitinib is an approved drug for the treatment of RA.This study is double-blinded means that…

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