Clinical Trial: A Phase 1-2 of ST316 With Selected Advanced Unresectable and Metastatic Solid Tumors
Study Status: Completed
Recruit Status: RECRUITING
Condition: Breast Cancer Metastatic
Study Type: INTERVENTIONAL
Official Title: A Phase 1-2 Dose-escalation and Expansion Study of ST316 in Subjects With Selected Advanced Unresectable and Metastatic Solid Tumors
Brief Summary:
This is an open-label, two-part, phase 1-2 study designed to determine the safety, tolerability, PK, pharmacodynamics (PD), and proof-of-concept efficacy of ST316 administered IV in subjects with selected advanced solid tumors likely to harbor abnormalities of the WNT/?-catenin signaling pathway.The study consists of two phases: a phase 1 dose escalation/regimen exploration phase and a phase 2 expansion phase.
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