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First received: August 31, 2023

Clinical Trial: Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Metastatic Triple-Negative Breast Cancer

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Metastatic Triple-Negative Breast Cancer

Study Type: INTERVENTIONAL


Official Title: ToPCourT: A Phase II Trial of Trilaciclib, Pembrolizumab, Gemcitabine and Carboplatin in Locally Advanced Unresectable or Metastatic Triple-Negative Breast Cancer (TNBC)

Brief Summary: The goal of this phase II study is to test the combination of trilaciclib, pembrolizumab, gemcitabine, and carboplatin in locally advanced unresectable or metastatic triple-negative breast cancer.The main questions it aims to answer are:to evaluate the anti-cancer efficacy (assess how well it works)to evaluate the safety and tolerability (how well the body can handle the treatment) of this combination of anti-cancer therapy

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