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First received: October 04, 2023

Clinical Trial: Preventing Injured Knees From osteoArthritis: Severity Outcomes

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Osteoarthritis, Knee

Study Type: INTERVENTIONAL


Official Title: Preventing Injured Knees From osteoArthritis: Severity Outcomes (PIKASO)

Brief Summary: This study is being done to find out if metformin is effective at reducing pain by delaying the onset of post-traumatic osteoarthritis (PTOA) after anterior cruciate ligament (ACL) reconstruction.This research study will compare metformin to placebo.The placebo tablet looks exactly like metformin, but contains no metformin.Placebos are used in research studies to see if the results are due to the study drug or due to other reasons.Metformin is approved by the U.S. Food and Drug Administration (FDA) to treat type…

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