Clinical Trial: Pioglitazone on Heart Failure in Type-2 Diabetes Mellitus Participants
Study Status: Completed
Recruit Status: RECRUITING
Condition: Type 2 Diabetes Mellitus in Obese
Study Type: INTERVENTIONAL
Official Title: Pioglitazone, Lipotoxicity, and Heart Failure With Preserved Ejection Fraction (HFpEF)
Brief Summary:
Our goal of the study is to learn the effects of the diabetes medication named Pioglitazone, in type-2 diabetic obese participants with Heart failure.The main question it aims to answer are:To demonstrate that impaired mitochondrial function leading to reduced ATP generation plays a key pathophysiologic role in the development of heart failure with preserved ejection fraction (HFpEF) in obese type 2 diabetic (T2D) individuals.To demonstrate that pioglitazone, improves diastolic (as well as systolic) function by…
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