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First received: August 28, 2023

Clinical Trial: Phase 2A Pilot C3 Trial of Recurrent/Refractory Metastatic Advanced Pancreatic Cancer

Study Status: Completed

Recruit Status: RECRUITING

Condition: Pancreatic Cancer Metastatic

Study Type: INTERVENTIONAL


Official Title: Phase 2A Pilot Trial of Metformin, Digoxin, Simvastatin (C3) in Combination With Gemcitabine in Subjects With Recurrent / Refractory Metastatic Advanced Pancreatic Cancer

Brief Summary: The goals of this trial are: 1) To evaluate the safety and tolerability of C3 administration with Gemcitabine; and 2) To assess the disease response following C3 administration with Gemcitabine.The main question it aims to answer are: 1) Is C3 in combination with Gemcitabine safe, tolerable, and effective for reducing improving advanced stage pancreatic cancer?and 2) Can C3 in combination with Gemcitabine prolong the lives of patients with advanced stage pancreatic cancer.Participants will receive a combination of…

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