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First received: November 06, 2023

Clinical Trial: Dexamethasone/Pancreatic Clamp P&F

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Insulin Resistance

Study Type: INTERVENTIONAL


Official Title: Role of Hyperinsulinemia in NAFLD: Dexamethasone-Pancreatic Clamp Pilot & Feasibility Study

Brief Summary: This is a single-center, prospective, randomized, controlled (crossover) clinical study designed to investigate the specific dose-response impact of insulin infusion rate (IIR) on blood glucose levels during a pancreatic clamp study in the setting of dexamethasone-induced insulin resistance.The investigators will recruit participants with a history of overweight/obesity but no history of prediabetes or diabetes.Participants will be rendered temporarily insulin resistant by taking seven doses of…

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