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First received: August 22, 2023

Clinical Trial: Personalized Real-Time DBS and PD Mechanisms

Study Status: Completed

Recruit Status: RECRUITING

Condition: Parkinson Disease

Study Type: INTERVENTIONAL


Official Title: Identifying Circuit Dynamics Underlying Motor Dysfunction in Parkinson's Disease Using Real-Time Neural Control

Brief Summary: A prospective cohort of patients scheduled to undergo deep brain stimulation (DBS) implantation surgery for the treatment of Parkinson's disease as per standard of care will be invited to participate in this study.This mechanistic study is aimed at better understanding the role of basal ganglia beta band (11-35 Hz) oscillations and resonance in the manifestation of Parkinson's disease (PD) motor signs using closed-loop electrical neurostimulation, levodopa medication, and computational modeling.The…

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