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First received: January 30, 2023

Clinical Trial: Effects of Administration of SCFA in Rheumatoid Arthritis Inadequate Responders

Study Status: Completed

Recruit Status: RECRUITING

Condition: Rheumatoid Arthritis

Study Type: INTERVENTIONAL


Official Title: A Pilot Proof of Concept Study of the Effects of Administration of a Short Chain Fatty Acid (SCFA) Supplement in Rheumatoid Arthritis Inadequate Responders (EASi-RAIR)

Brief Summary: This study is a pilot, proof of concept study to determine the effects of administering an oral short-chain fatty acid (SCFA) supplement to Rheumatoid Arthritis (RA) patients with inadequate response to methotrexate (MTX).The study will include up to 35 participants to obtain a sample size of at least 25 participants taking the oral supplement.The researchers hypothesize that oral SCFA will change the participants' gut microbiome and regulatory immune responses.Clinical data to assess for adverse events,…

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