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First received: July 24, 2023

Clinical Trial: The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

Study Status: Completed

Recruit Status: RECRUITING

Condition: Obesity

Study Type: INTERVENTIONAL


Official Title: The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function

Brief Summary: Obesity is associated with increased cardiometabolic disease risk due, in part, to heightened chronic inflammation arising from adipose tissue.There are no current targeted therapies to prevent or reverse the chronic inflammation of obesity, and a better understanding of these inflammatory pathways in humans is key to future therapeutic interventions.This trial will determine both the anti-inflammatory potential of the SGLT2 inhibitor empagliflozin, and the contribution of adipose inflammation to surrogate…

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