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First received: September 18, 2023

Clinical Trial: Biomarkers of Reaction To HIIT Exercise

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Stroke

Study Type: INTERVENTIONAL


Official Title: What Makes a Responder, a Responder? Biomarkers to Help Identify Responders and Resistors to High-intensity Interval Training for Lower Extremity Chronic Stroke

Brief Summary: Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy.However, some individuals may not respond to HIIT even when fully adherent to the program.To address this, the investigators propose to build a predictive model that identifies if a Veteran with chronic subcortical stroke will improve their walking speed with HIIT by incorporating blood lactate as an early predictor of exercise response, and inhibitory neurotransmitter…

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