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First received: January 19, 2023

Clinical Trial: Trial to Model Primary, Secondary, and Tertiary Dengue Using a Monovalent Vaccine

Study Status: Completed

Recruit Status: RECRUITING

Condition: Response To Dengue Exposure

Study Type: INTERVENTIONAL


Official Title: Phase 1 Trial to Model Primary, Secondary, and Tertiary Dengue Using a Monovalent Vaccine

Brief Summary: Background:Dengue is a disease caused by a virus transmitted by mosquitoes in tropical and subtropical regions.Dengue is a leading cause of hospital stays and death in parts of Asia and Latin America, and outbreaks have occurred in the US.Currently, only one vaccine is licensed for dengue, but it only protects people who have had dengue before.In people who have never had dengue, that vaccine increases the risk of severe disease.Better vaccines are needed.Objectives:To test a potential new vaccine against…

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