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First received: March 20, 2023

Clinical Trial: Investigating the Use of Intravenous Tranexamic Acid in Gender Affirming Mastectomy

Study Status: Completed

Recruit Status: RECRUITING

Condition: Postoperative Hematoma

Study Type: INTERVENTIONAL


Official Title: Investigating the Use of Intravenous Tranexamic Acid in Gender Affirming Mastectomy

Brief Summary: Gender affirming surgeries (GAS) have been steadily increasing in the US, with the gender affirming mastectomy (GAM) being the most common surgery performed.Complications associated with these surgeries include hematoma and seroma.Prior studies in orthopedics, plastic surgery, and trauma have shown significant reduction of bleeding and ecchymosis with the use of tranexamic acid (TXA).TXA is a synthetic amino acid that blocks plasminogen conversion to plasmin, to stabilize clot formation.The intravenous (IV)…

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