Clinical Trial: 19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease
Study Status: NOT_YET_RECRUITING
Recruit Status: NOT_YET_RECRUITING
Condition: Cystic Fibrosis in Children
Study Type: OBSERVATIONAL
Official Title: A Cross-sectional Pilot Study of 19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease
Brief Summary:
This study capitalizes on the emerging technology of 19F MRI, using conventional 'thermally' polarized perfluorinated gas (perfluoropropane, or PFP) mixed with oxygen and studied with magnetic resonance imaging (MRI) to visualize ventilation.This technique has not been studied in children.Children and adolescents (6-17 years old) with cystic fibrosis (CF) who have normal spirometry will undergo 19F MRI with the inhalation of an inert contrast gas to study ventilation.Comparisons will be made to a cohort…
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