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First received: September 20, 2023

Clinical Trial: 19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Cystic Fibrosis in Children

Study Type: OBSERVATIONAL


Official Title: A Cross-sectional Pilot Study of 19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease

Brief Summary: This study capitalizes on the emerging technology of 19F MRI, using conventional 'thermally' polarized perfluorinated gas (perfluoropropane, or PFP) mixed with oxygen and studied with magnetic resonance imaging (MRI) to visualize ventilation.This technique has not been studied in children.Children and adolescents (6-17 years old) with cystic fibrosis (CF) who have normal spirometry will undergo 19F MRI with the inhalation of an inert contrast gas to study ventilation.Comparisons will be made to a cohort…

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