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First received: October 02, 2023

Clinical Trial: Adolescent Mood During Puberty and Testosterone

Study Status: Completed

Recruit Status: RECRUITING

Condition: Adolescent Depression

Study Type: INTERVENTIONAL


Official Title: Probing the Neurophysiological Mechanisms Underlying Sex-specific Testosterone-mood Relationships During Puberty: A Randomized Controlled Trial Using a Smartphone-based Training Program

Brief Summary: Starting at puberty, female adolescents are nearly three-times more likely to develop internalizing disorders, like depression, while male adolescents are two-times more likely to develop externalizing disorders, like attention deficit hyperactivity disorder (ADHD).This divergence between the sexes during puberty suggests sex-specific pathways of risk and differential effects of sex hormones.The purpose of this research is to determine: 1) sex-specific neural and endocrine features of the pubertal transition that…

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