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First received: September 13, 2023

Clinical Trial: Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients

Study Status: NOT_YET_RECRUITING

Recruit Status: NOT_YET_RECRUITING

Condition: Cytomegalovirus Infections

Study Type: INTERVENTIONAL


Official Title: Open Label Trial of Tolerability and Efficacy of Oral Letermovir for CMV Prophylaxis Among Heart and Lung Transplant Recipients

Brief Summary: Open label study to determine tolerability and efficacy of letermovir for CMV prophylaxis in heart and lung transplant recipients and compare it to the efficacy of valganciclovir historical controls.The study hypotheses are:Letermovir prophylaxis will be associated with similar rates of CMV infection as valganciclovir among heart and lung transplant recipientsLetermovir will be better tolerated than valganciclovir for CMV prophylaxis in heart and lung transplant recipients, with a higher proportion of days of…

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