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First received: January 21, 2023

Clinical Trial: Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Study

Study Status: Completed

Recruit Status: RECRUITING

Condition: Tourette Syndrome

Study Type: INTERVENTIONAL


Official Title: Strengthening Tourette Treatment OPtions Using TMS to Improve CBIT, a Double-blind, Randomized, Controlled Study

Brief Summary: This pilot study will investigate the clinical and neurophysiological effects of repetitive transcranial magnetic stimulation (rTMS) followed by comprehensive behavioral intervention for tics (CBIT) in adult patients with Tourette's Syndrome (TS).Two groups of moderate disease severity will be randomized to receive active or sham rTMS targeted to the supplementary motor area (SMA) followed by eight CBIT sessions.The change in tic frequency and severity (primary outcome) and neurophysiological changes…

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