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First received: March 27, 2023

Clinical Trial: A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome

Study Status: Completed

Recruit Status: RECRUITING

Condition: Cushing Syndrome

Study Type: INTERVENTIONAL


Official Title: A Phase 1b/2a Open-label Multiple-ascending Dose Exploratory Study of CRN04894 in ACTH-dependent Cushing's Syndrome (Cushing's Disease or Ectopic ACTH Syndrome)

Brief Summary: A Phase 1b/2a, first-in-disease, open-label, multiple-ascending dose exploratory study to evaluate safety, tolerability, pharmacokinetics (PK), and pharmacodynamic biomarker responses associated with CRN04894 (an adrenocorticotropic hormone [ACTH] receptor antagonist) in participants with ACTH-dependent Cushing's syndrome (Cushing's disease or Ectopic ACTH Syndrome [EAS])

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