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First received: January 12, 2023

Clinical Trial: Transcutaneous Vagus Nerve Stimulation (tcVNS) in JIA

Study Status: Completed

Recruit Status: RECRUITING

Condition: Juvenile Idiopathic Arthritis (JIA)

Study Type: INTERVENTIONAL


Official Title: Using the Cholinergic Anti-Inflammatory Pathway to Treat Juvenile Idiopathic Arthritis (AJA01)

Brief Summary: The study is a multicenter, double-blind, sham-controlled trial to evaluate the safety and effectiveness of tcVNS on pain and inflammation associated with JIA.tcVNS is administered with a device that gives off mild electrical impulses through the skin to stimulate the vagus nerve.Part of the vagus nerve and its branches are located in the head and neck.For this study, the impulses will be administered in areas overlying the vagus nerve using a small electrode.The electrode helps to conduct the stimulation through…

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