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First received: March 08, 2023

Clinical Trial: MCW Alpha/Beta T-Cell and B-Cell Depletion With Targeted ATG Dosing

Study Status: Completed

Recruit Status: RECRUITING

Condition: Leukemia

Study Type: INTERVENTIONAL


Official Title: Matched Unrelated Donor and Partially Matched Related Donor Peripheral Stem Cell Transplantation With Alpha/Beta T-Cell and B-Cell Depletion for Patients With Hematologic Malignancies With Target

Brief Summary: This is a single arm pilot study for patients with hematologic malignancies receiving unrelated or haploidentical related mobilized peripheral stem cells (PSCs) using the CliniMACS system for alpha/beta T cell depletion plus CD19+ B cell depletion with individualized ALC-based dosing of ATG to study impact on engraftment, GVHD, and disease free survival

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