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First received: June 28, 2023

Clinical Trial: Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Study Status: Completed

Recruit Status: RECRUITING

Condition: Stage III Prostate Cancer AJCC v8

Study Type: INTERVENTIONAL


Official Title: The Phase III 'High Five Trial' Five Fraction Radiation for High-Risk Prostate Cancer

Brief Summary: This phase III trial compares stereotactic body radiation therapy (SBRT), (five treatments over two weeks using a higher dose per treatment) to usual radiation therapy (20 to 45 treatments over 4 to 9 weeks) for the treatment of high-risk prostate cancer.SBRT uses special equipment to position a patient and deliver radiation to tumors with high precision.This method may kill tumor cells with fewer doses over a shorter period of time.This trial is evaluating if shorter duration radiation prevents cancer from coming…

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