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First received: January 10, 2024

Clinical Trial: Bace1as Role in Heart Failure (BACE1AS-HF)

Study Status: Completed

Recruit Status: RECRUITING

Condition: Heart Failure

Study Type: OBSERVATIONAL


Official Title: Role of the BACE1-AS Long Noncoding RNA in Ischemic Heart Failure

Brief Summary: The objective of this project is 1) to explore the clinical relevance of BACE1-AS and BACE1 as therapeutic targets and 2) to evaluate their potentiality as biomarkers in ischemic heart failure (HF).The first aim will be studied by validating in left ventricle biopsies in patients with post-ischemic heart failure the transcriptome and DNA methylation status data obtained in cell lines where the expression of BACE1-AS has been modulated.The investigation of BACE1-AS and BACE1 as biomarkers will be obtained by using…

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