Clinical Trial: A Microneurography Study of NaV1.8 Inhibition in Healthy Adults
Study Status: COMPLETED
Recruit Status: COMPLETED
Condition: Pain
Study Type: INTERVENTIONAL
Official Title: A Phase 1, Randomized, Double-blind, Placebo-controlled, Parallel Study Evaluating the Effects of Single Doses of NaV1.8 Inhibitors on C-Nociceptor Action Potentials in Healthy Adults
Brief Summary:
The purpose of this study is to determine the effects of Nav1.8 inhibition on activity-dependent slowing (ADS) of C-nociceptor nerve fibers, evoked action potential (AP) conduction velocity of C-nociceptor nerve fibers using VX-150 and VX-548.
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