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First received: April 03, 2025

Clinical Trial: Evaluation of Different Scaffolds in Regenerative Endodontic Treatment

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Endodontic Disease

Study Type: INTERVENTIONAL


Official Title: Evaluation of Different Scaffolds in Regenerative Endodontic Treatment of Immature Non-Vital Permanent Teeth and Their Release of Growth Factors: A Randomized Clinical Trial

Brief Summary: The aim of this study is to evaluate and compare the regenerative potentials of Injectable Platelet-Rich Fibrin (I-PRF), Platelet-Rich Fibrin (PRF), and Blood Clot (BC) as different scaffolds regarding:Radiographic outcomes (increase of root length, increase in thickness of dentinal wall, healing of periapical lesion, and apical closure).Clinical outcomes in the treatment of young, immature permanent teeth with necrotic pulps.

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