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First received: March 21, 2025

Clinical Trial: Functional Connectome in Prader-Willi Syndrome: Neuroimaging and AI to Assess Therapeutic Impact

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Prader Willi Syndrome

Study Type: OBSERVATIONAL


Official Title: Characterization of the Functional Connectome in Prader-Willi Syndrome: Integrating Neuroimaging and Artificial Intelligence to Assess the Impact of Physiological and Therapeutic Interventions

Brief Summary: The goal of this observational study is to explore brain network changes and identify patterns related to hyperphagia, hormonal treatment effects, and cognitive deficits in adults with Prader-Willi Syndrome (PWS).The main questions it aims to answer are:How are brain connectivity patterns altered in PWS patients compared to healthy and obese controls?How do brain network changes relate to hyperphagia and the response to growth hormone therapy?Researchers will compare PWS patients to healthy and obese controls to…

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