Clinical Trial: Photodynamic Therapy in Root Canal Treatment of T2DM Patients: Microbiome Analysis Via Next-Gen Sequencing
Study Status: COMPLETED
Recruit Status: COMPLETED
Condition: Type 2 Diabetes Mellitus (T2DM)
Study Type: INTERVENTIONAL
Official Title: Evaluation of the Effectiveness of Root Canal Treatment Performed Using Photodynamic Therapy in Teeth With Apical Periodontitis in Patients With Type 2 Diabetes Through Next-Generation Sequencing Micr
Brief Summary:
This clinical study investigates the effectiveness of antimicrobial photodynamic therapy (aPDT) as an additional disinfection method in root canal treatment of patients with Type 2 Diabetes Mellitus (T2DM) who have apical periodontitis (AP).T2DM is known to negatively impact the healing of periapical tissues due to impaired immune response.In this study, methylene blue is used as a photosensitizer, activated by a specific wavelength of light to eliminate residual bacteria that are difficult to reach with…
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