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First received: April 01, 2025

Clinical Trial: Comparison of Different Methods for Measuring Urinary Oxalate and Citrate: An Observational Study

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Hyperuricosuria

Study Type: OBSERVATIONAL


Official Title: Novel Derivatization-Based HPLC for Urinary Oxalate and Citrate: A Superior Clinical Alternative to Ion Chromatography

Brief Summary: This observational study aims to compare three different laboratory methods for measuring urine oxalate and citrate concentrations.The primary objective is to evaluate whether an improved High-Performance Liquid Chromatography (HPLC) method-using a novel derivatization reagent-can achieve similar accuracy to the gold standard Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS) while offering advantages in cost, speed, and ease of use in routine clinical settings.The study will involve the collection of…

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