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First received: February 16, 2023

Clinical Trial: Jejunal Ketogenesis and Type 2 Diabetes

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Obesity, Morbid

Study Type: INTERVENTIONAL


Official Title: Small Intestinal Ketogenesis - Potential Significance for Type 2 Diabetes in Obesity

Brief Summary: The goal of this cross-over study in obese subjects is to learn about the common co-morbidity type 2 diabetes and the local formation of ketone bodies.The type of study is an exploratory trial with the participants as own controls.The main questions it aims to answer are: 1.Does food intake-induced ketogenesis exist in the small intestine of obese individuals?2. Are insulin resistance, the incretin GLP-1 release and the glucose transporter SGLT1 affected in obese individuals without type 2 diabetes in the same way…

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