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First received: July 13, 2025

Clinical Trial: Use of Injectable Extended Platelet-Rich Fibrin as a Local Drug Delivery in the Treatment of Stage II Periodontitis Patients

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Periodontitis Stage II

Study Type: INTERVENTIONAL


Official Title: Use of Injectable Extended Platelet-Rich Fibrin as a Local Adjunctive Therapy in the Treatment of Stage II Periodontitis Patients (Randomized Controlled Clinical Trial)

Brief Summary: The objective of the present study is to assess the clinical effectiveness of local delivery of injectable extended platelet-rich fibrin in subgingival application when used in conjunction with scaling and root planing (SRP) in the treatment of stage II periodontitis.The primary outcome includes the clinical attachment gain after 6 months, whereas the secondary outcomes include the changes of probing pocket depth, bleeding on probing percentage, plaque and gingival indices and the concentration of matrix…

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