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First received: July 14, 2025

Clinical Trial: Ketogenic vs. Mediterranean Diet on Metabolic and Hormonal Parameters in Patients With Active Acromegaly

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Acromegaly

Study Type: INTERVENTIONAL


Official Title: The Effect of a Ketogenic vs. Mediterranean Diet on Metabolic and Hormonal Parameters in Patients With Active Acromegaly: A Prospective Crossover Study

Brief Summary: This prospective, single-center, crossover study aims to evaluate the metabolic and hormonal effects of a ketogenic diet compared to a Mediterranean diet in patients with active acromegaly.Thirty-five adult patients with biochemically confirmed active acromegaly will undergo a three-week ketogenic diet followed by a three-week Mediterranean diet, with a two-week transitional phase.The primary outcome is the change in serum IGF-1 levels.Secondary outcomes include changes in anthropometric, biochemical, and…

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