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First received: November 30, 2025

Clinical Trial: Postbiotic Intervention on Vaginal Microbiota

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Infertile Women Undergoing IVF or ICSI

Study Type: INTERVENTIONAL


Official Title: To Investigate the Effect of Postbiotic Intervention on Vaginal Microbiota in Infertile Women

Brief Summary: This study investigates the effects of postbiotic intervention on vaginal microbiota in infertile patients.Using a pre-post test design, we will enroll 15 women aged 30-45 years with at least two IVF failures.Participants will receive postbiotic intervention for 8 weeks.Vaginal secretion samples will be collected before and after treatment for 16S rRNA sequencing analysis to assess microbial composition, dominant species distribution, ?-diversity index, and Lactobacillus content.Primary outcomes include changes in…

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