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First received: November 18, 2025

Clinical Trial: Comparison of Propofol and Ketofol as Induction Agents for Electroconvulsive Therapy

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Major Depressive Disorder

Study Type: INTERVENTIONAL


Official Title: A Randomized Controlled Trial Comparing Propofol and Ketofol for Hemodynamic Stability During Electroconvulsive Therapy

Brief Summary: This randomized controlled trial will compare two anesthetic agents, propofol and ketofol (a combination of propofol and ketamine), in patients undergoing electroconvulsive therapy (ECT).Propofol is commonly used but may lower blood pressure, while ketofol may help maintain more stable cardiovascular function.The study will evaluate changes in systolic blood pressure following ECT when either propofol or ketofol is used for anesthesia induction.A total of 80 adult patients will be enrolled and randomly assigned to…

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