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First received: March 12, 2026

Clinical Trial: Re-bleeding in Giant Meningioma and Intraoperative Hydroxyethyl Starch (HES) Fluid Therapy

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Meningioma of Brain

Study Type: OBSERVATIONAL


Official Title: Re-bleeding in Giant Meningioma and Intraoperative Hydroxyethyl Starch (HES) Fluid Therapy: A Retrospective Cohort Study

Brief Summary: Project Summary: Retrospective Cohort StudyCore ObjectiveThe primary goal is to determine if the volume of Hydroxyethyl Starch (HES) 130/0.4(specifically Voluven® or Volulyte®) administered during the removal of giant meningiomas (tumors > 5 cm) increases the risk of postoperative complications.Research QuestionDoes the volume of intraoperative HES solution influence the rate of re-bleeding (requiring a second surgery within 48 hours) or the development of Acute Kidney Injury (AKI) within 7 days after the…

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