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First received: June 20, 2024

Clinical Trial: Melatonin fOr CHronic bAck Pain (The MOCHA Trial)

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Back Pain Lower Back Chronic

Study Type: INTERVENTIONAL


Official Title: Melatonin fOr CHronic bAck Pain (The MOCHA Trial): A Randomized, Double Blind, Placebo-controlled Trial

Brief Summary: According to the World Health Organization (WHO) Global Burden of Disease study, back pain is one of the conditions impacting disability the most worldwide.Pain medication use in patients with chronic back pain is substantial, but the efficacy of commonly used analgesics such as paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs), muscle relaxants and opioids compared with placebo are modest, with effects typically less than 10 points on a 0-100 pain scale.Importantly, these analgesics are not harmless due…

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