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First received: June 09, 2026

Clinical Trial: Oncology Treatment Related Ocular Surface Changes

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Breast Neoplasm, Exercise

Study Type: OBSERVATIONAL


Official Title: Ophthalmological Examination of Changes Induced by Therapy and Ocular Surface Abnormalities in Patients With Cancer

Brief Summary: clinical trialThe goal of this clinical trial is to learn if drug trastuzumab works to treat HER2 positive mamma carcinomas without causing dry eye related ocular surface changes in adults. The main questions it aims to answer are:Does trastuzumab increase the dry eye related subjective symptoms? Does trastuzumab cause increased tear film instability and corneal epithelial staining (Oxford score), and lipid layer deterioration? Is a dose-dependent ocular surface effect identifiable attributable to trastuzumab and…

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