Clinical Trial: Insulin Intratympanic Application
Study Status: COMPLETED
Recruit Status: COMPLETED
Condition: Tympanic Membrane Perforation
Study Type: INTERVENTIONAL
Official Title: Topical Insulin Insitu-gel as a Wound Healing Accelerator and Anti-inflammatory Agent for Persistent Suppurative Otitis Media in RCT
Brief Summary:
The objective of the present study was to study the impact of insulin insitu-gel formulation on healing progress after surgical procedures for treatment of dry tympanic membrane perforation for at least three consecutive months. At the beginning, an insulin insitu-gel was prepared from three different polymers compatible with insulin physiochemically and reported to be vain on insulin efficacy or safety. Insulin insitu-gel was prepared using chitosan, polyvinyl alcohol, and Pluronic F127 with glycerol as a…
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