Clinical Trial: A Study of the Safety of Mibavademab in Pediatric and Adult Participants Switching From Metreleptin to Mibavademab for the Treatment of Generalized Lipodystrophy (GLD)
Study Status: COMPLETED
Recruit Status: COMPLETED
Condition: Generalized Lipodystrophy
Study Type: INTERVENTIONAL
Official Title: A Single-Arm, Open-Label, Safety Study in Patients With Generalized Lipodystrophy Switching From Metreleptin to Mibavademab, A Leptin Receptor Agonist Antibody
Brief Summary:
This study is researching an experimental drug called mibavademab. The study is focused on participants with GLD who have been on metreleptin treatment for at least 6 months with no change in dose for the last 3 months.The aim of the study is to see how safe and tolerable mibavademab is when switching from treatment with metreleptin.The study is looking at several other research questions, including:* What side effects may happen from taking mibavademab* How much mibavademab is in the blood at different times*…
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