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First received: August 19, 2026

Clinical Trial: Patient Comfort Following Intravitreal Injections Using Iheezo Versus Standard Anesthesia

Study Status: COMPLETED

Recruit Status: COMPLETED

Condition: Macular Degeneration
Diabetic Retinopathy
Retinal Vein Occlusion (RVO)

Study Type: INTERVENTIONAL


Official Title: Comparative Evaluation of Patient Comfort Following Intravitreal Injections Using Iheezo Versus Standard Anesthesia in a Private Retina Practice

Brief Summary: Prospective comparative clinical study.One hundred eyes of 50 patients were included. All patients received bilateral same-day intravitreal injections, with Iheezo administered to only one randomly selected eye and standard topical anesthesia administered to the contralateral control eye. Ocular discomfort was assessed using a 0-10 numeric rating scale at 2 minutes, 1 hour, 6-12 hours, and 24 hours following injection. The primary longitudinal analysis used a linear mixed-effects model incorporating treatment…

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