Research Article: Assessing the impact of enteral nutrition on peripancreatic exudate in acute pancreatitis using CT volume measurement
Abstract:
To investigate the effect of enteral nutrition (EN) on peripancreatic exudate in MSAP and SAP patients using CT volume measurement. This retrospective study included 328 patients diagnosed with MSAP and SAP from October 2017 to June 2023. Patients were divided into EN and non-EN groups and further stratified into acute peripancreatic fluid collection (APFC) and acute necrotic collection (ANC) groups based on local complications. Abdominal CT images obtained within 24 h of admission and within 15 days after therapy were analyzed using Itk-Snap software to outline and calculate peripancreatic exudate volumes. Volume differences before and after therapy were compared between groups. A 1 year follow-up was conducted to compare the time of complete resolution of peripancreatic exudate between groups. After EN therapy, patients have significantly less peripancreatic exudate than those who do not receive EN. In the APFC and ANC groups, EN was associated with a greater reduction in exudate than that in the non-EN group. The time to complete resolution of exudate was shorter in the EN group than in the non-EN group. EN promotes the absorption of peripancreatic exudate and improves the prognosis of patients with MSAP and SAP.
Introduction:
Acute pancreatitis (AP) is a complex and varied disease with an overall increase in incidence of 3.07% per year ( 1 ). A total of 80% of patients develop mild acute pancreatitis (MAP), which can be cured by fluid resuscitation, nutritional support therapy and other therapies ( 2 , 3 ). The remaining 20% of severely ill patients are characterized by pancreatic necrosis or distal organ failure and are expected to require intensive care and possible surgical intervention, with mortality rates up to 20% ( 3 , 4 ). In…
Read more