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Research Articles Search

Showing 1,060 of 147,163 result(s)
Polyfunctionality of CD4 + T lymphocytes in buffaloes and cattle: comparative antigen-specific cytokine responses in bovine tuberculosis infection

Abstract: Bovine tuberculosis (BTB), caused by Mycobacterium bovis , is a chronic infectious disease of major veterinary and public health concern. It affects a broad range of…

Date: 2025-10-01

Serum neurofilament light chain levels in myasthenia gravis patients with and without symptoms

Abstract: This study aimed to investigate serum neurofilament light chain (sNFL) levels in patients with myasthenia gravis (MG) and explore its potential as a biomarker for…

Date: 2025-10-01

Mesenchymal stem cells enhanced with SeNPs protection against CLP induction associated with liver injury are mediated via antioxidant, anti-inflammatory, and immunomodulatory activities

Abstract: Sepsis-induced liver injury is a serious issue in critical care. Since antibiotics are insufficiently effective to combat the disease and avoid upcoming organ failure,…

Date: 2025-10-01

Inhibition of IL-27 signaling regulates chemokine levels and sustains CXCR2 receptor expression on mononuclear cells to improve disease outcomes during gram-negative neonatal sepsis

Abstract: Interleukin-27 (IL-27) is a cytokine that belongs to the IL-6/IL-12 cytokine family with diverse influences on the immune response. Elevated levels of IL-27 cytokine…

Date: 2025-10-01

Loss of ATG5 impairs CD4+ T cell activation and promotes anti-tumor responses

Abstract: Macroautophagy (hereafter called autophagy) is an ancient catabolic process that delivers bulky cargo to lysosomal degradation. The autophagic pathway is regulated by…

Date: 2025-10-01

Phase-specific mortality risk of serum lactate thresholds in very low birth weight infants with late-onset sepsis: a retrospective cohort study

Abstract: Late-onset sepsis (LOS) in very low birth weight (VLBW) infants confers substantial mortality risk. While lactate monitoring is standard, validated prognostic thresholds…

Date: 2025-10-01

IONPs combined with cytarabine downregulated IFITM3 expression to inhibit acute myeloid leukemia

Abstract: Acute myeloid leukemia (AML) is the most prevalent acute leukemia in adults. While conventional therapies can induce remission disease frequently relapses with fatal…

Date: 2025-10-01

Chronic stress synergizes with Listeria monocytogenes to promote intestinal adenomagenesis via myeloid-derived suppressor cells

Abstract: Chronic stress and gut dysbiosis are established risk factors for colorectal adenocarcinoma, yet their synergistic effects on the development of intestinal precancerous…

Date: 2025-10-01

Research paper efficacy and safety of telitacicept combined with standard therapy for lupus nephritis: a single-center real-world study

Abstract: Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus with suboptimal response to standard therapy. This study evaluated the efficacy and safety…

Date: 2025-10-01

Hypocomplementemia dynamics during tocilizumab therapy in systemic juvenile idiopathic arthritis: a retrospective longitudinal study

Abstract: This study aimed to investigate the trajectory of complement C3 and C4 levels during tocilizumab (TCZ) treatment in patients with systemic juvenile idiopathic arthritis…

Date: 2025-10-01