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Research Articles Search

Showing 1,130 of 147,163 result(s)
Targeted and personalized immunotherapy in lung adenocarcinoma: single-cell RNA sequencing of MAFF + tumor cells and the therapeutic potential of FOS

Abstract: Non-small cell lung cancer (NSCLC) was a major cause of cancer-related mortality globally. Despite advancements in immunotherapy and targeted therapies, clinical…

Date: 2025-08-27

Integration of single-cell and bulk RNA sequencing to identify unique tumor stem cells and construct novel prognostic markers for assessing ESCA prognosis and drug sensitivity

Abstract: Cancer stem cells (CSCs) are crucial contributors to the development and progression of esophageal cancer (ESCA). This study utilized single-cell RNA sequencing…

Date: 2025-08-27

Real-world cardiovascular risks of ibrutinib in chronic lymphocytic leukemia: a retrospective study

Abstract: Ibrutinib has made significant contributions to the treatment of chronic lymphocytic leukemia (CLL) with recognized cardiovascular toxicities in some patients. This…

Date: 2025-08-26

The impact of oral semaglutide on glycemic control and weight reduction: a database analysis of dosing effects in Japanese individuals with type 2 diabetes

Abstract: GLP-1 receptor agonists (GLP-1 RAs) reduce cardiovascular events in type 2 diabetes (T2D), and oral formulations improve accessibility. However, their real-world…

Date: 2025-08-26

Alcohol consumption, high-sensitivity C-reactive protein, and estimated glomerular filtration rate: tripartite predictors of 10-year cardiovascular risk progression in patients with type 2 diabetes mellitus after COVID-19

Abstract: To investigate the predictors influencing the advancement of 10-year cardiovascular disease (CVD) risk after infection with Corona Virus Disease 2019 (COVID-19) in type…

Date: 2025-08-26

Cardiovascular risk after total thyroidectomy in patients with differentiated thyroid carcinoma undergoing levothyroxine replacement monotherapy

Abstract: Prospective studies have demonstrated the favorable prognosis of differentiated thyroid cancer, primarily due to its low risk of recurrence and mortality. Considering…

Date: 2025-08-26

Association between dietary selenium intake and the prevalence of prediabetes in Newfoundland population: a cross-sectional study

Abstract: Emerging evidence highlights the role of selenium (Se) in glucose metabolism through selenoprotein-mediated antioxidant and anti-inflammatory pathways. However,…

Date: 2025-08-26

Effect of levothyroxine on major adverse cardiovascular events in patients with hypothyroidism and cardiovascular disease

Abstract: This study aimed to evaluate the effectiveness of levothyroxine, compared to non-levothyroxine treatment, in preventing adverse cardiovascular events and mortality in…

Date: 2025-08-26

An impact of type 2 diabetes mellitus on NKT-like cell population in humans: a new insight into impaired immune response in hyperglycemia

Abstract: Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by insulin resistance and pancreatic ?-cell dysfunction. T2DM is associated with increased…

Date: 2025-08-26

Impact of dietary patterns on body weight in girls with central precocious puberty treated with leuprolide during the COVID-19 pandemic

Abstract: To evaluate the nutritional status and dietary patterns of girls with central precocious puberty (CPP) undergoing treatment with leuprolide acetate during the COVID-19…

Date: 2025-08-26