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Community health workers’ knowledge and attitudes toward advance directives in China: a cross-sectional study

Abstract: Advance Directives (ADs), including living wills and durable powers of attorney for healthcare, are vital to uphold patient autonomy in end-of-life care, reducing family…

Date: 2025-09-12

Compound heterozygous mutations in MICU1 cause myopathy with extrapyramidal signs in two Chinese pedigrees

Abstract: Although MICU1 -related myopathy with extrapyramidal signs (MPXPS) has been reported globally, its genotypic and phenotypic spectrum in Chinese populations remains…

Date: 2025-09-12

Antimicrobial susceptibility profiles of Escherichia coli isolates from domestic pigeons in Hungary

Abstract: This cross-sectional observational study aimed to determine the antimicrobial susceptibility profiles of Escherichia coli isolates from domestic pigeons (Columba livia…

Date: 2025-09-12

Albumin: a mediator of the association between serum calcium and triglyceride-glucose index among Chinese individuals with osteoporotic fractures

Abstract: Osteoporotic fractures (OPFs) are a major global health concern, affecting nearly 200 million individuals worldwide. Notably, patients with type 2 diabetes mellitus…

Date: 2025-09-12

Therapeutic potential of luteolin in central precocious puberty: insights from a danazol-induced rat model

Abstract: Recently, central precocious puberty (CPP) is becoming a major public health concern worldwide due to its enhanced prevalence. Traditional Chinese medicine (TCM)…

Date: 2025-09-12

OvaRePred (HerTempo): an enhanced ovarian aging clock for personalized reserve assessment, endocrine age modeling, and predicting reproductive milestones across the female lifecycle

Abstract: Women display marked variability in ovarian reserve, which is pivotal for fertility and menopausal timing. Traditional criteria, such as Bologna and Poseidon, classify…

Date: 2025-09-12

6-gingerol promotes apoptosis of ovarian cancer cells through miR-506/Gli3 signaling pathway activation

Abstract: Ginger rhizomes have shown potential for promoting human health, including the prevention and treatment of cancer. Here, we investigated the anticancer activities of…

Date: 2025-09-12

Acanthosis nigricans and acrochordons as clinical markers of metabolic disturbance during pregnancy: a prospective cohort study

Abstract: This study investigated the prevalence of acanthosis nigricans and acrochordons as potential markers of diabetes or insulin resistance in diabetic and non-diabetic…

Date: 2025-09-12

Lipocalin-2 in preoperative cerebrospinal fluid is a biomarker for postoperative delirium after hip fracture surgery in older adults: a prospective cohort study

Abstract: Postoperative delirium (POD) is a common central nervous system complication in older adult surgical patients. At present, the mechanism for POD is still unclear.…

Date: 2025-09-12

Medication adherence in obsessive-compulsive disorders and evaluation of effective adherence support strategies

Abstract: Medication adherence is a critical component in the treatment of psychiatric conditions such as obsessive-compulsive disorder (OCD). Poor adherence is associated with an…

Date: 2025-09-12