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Association of serum 25-hydroxyvitamin D levels with age-related macular degeneration and its clinical correlates: a cross-sectional study

Abstract: Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in older adults, with significant inter-individual variability in clinical…

Date: 2025-08-14

Global trends and inequalities in eye cancer burden: a comprehensive analysis based on the global burden of disease study

Abstract: Eye cancer is a significant threat to vision and survival because of its location, diagnostic challenges, and aggressive nature. However, its global epidemiology,…

Date: 2025-08-14

Elevated serum IL-10/IL-6 ratio as a novel biomarker for secondary central nervous system lymphoma and poor prognosis in DLBCL

Abstract: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma and carries a poor prognosis when it involves the central nervous system (CNS),…

Date: 2025-08-13

Implementing comprehensive geriatric assessment in an academic hematologic outpatient setting: experiences from medical doctors and patients

Abstract: The incidence of most cancers increases with age and cancer is a leading cause of morbidity and mortality in the older population. Older cancer patients frequently have…

Date: 2025-08-13

Diagnostic and therapeutic pathways for lymphoma patients: expert consensus through Nominal Group Technique and Delphi methodology

Abstract: Lymphomas encompass a heterogeneous group of B- and T-cell malignancies necessitating a complex and precise management. With the aim to define standardized diagnostic…

Date: 2025-08-13

Iron overload promotes myeloid differentiation of normal hematopoietic stem cells and educates macrophage mediated immunosuppression in acute myeloid leukemia

Abstract: The hematopoietic ecosystem comprises both cellular components such as hematopoietic stem cells (HSCs) and immune cells as well as non-cellular components including…

Date: 2025-08-13

Reporting of immune-related adverse events in US Food and Drug Administration approvals of immune checkpoint inhibitors

Abstract: Predicting the occurrence of immune-related adverse events (irAEs) related to immune checkpoint inhibitors (ICI) is complex. Monitoring of irAEs is critical as…

Date: 2025-08-13

Correlation between different levels of thyroid autoantibodies and immune checkpoint inhibitor-associated thyroid dysfunction

Abstract: To investigate the correlation between thyroid immune-related adverse events (irAEs) and thyroid autoantibodies in cancer patients treated with immune checkpoint…

Date: 2025-08-13

Distinct NK cell function and gene expression in children with acute lymphoblastic leukemia in remission before and after acute exercise: an exploratory study

Abstract: Brief bouts of exercise mobilize natural killer (NK) cells and influence their function and gene expression in adults. However, little is known about these effects in…

Date: 2025-08-13

Use of multiple metrics and clustering analysis to assess antimicrobial use in Shanxi hospitals, China: a cross-sectional study based on 25 general hospitals

Abstract: To investigate the current patterns of antimicrobial use among nonsurgical inpatients across 25 general hospitals in Shanxi Province and to evaluate the antimicrobial…

Date: 2025-08-13