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Research Articles Search

Showing 50 of 147,163 result(s)
Growth hormone therapy and chromosomal mosaicism in turner syndrome: 25 years of growth outcomes in Taiwan

Abstract: Turner syndrome (TS), a chromosomal disorder affecting females, is commonly associated with short stature due to haploinsufficiency of the SHOX gene. Recombinant human…

Date: 2025-10-29

Effects of Long-term low-dose intermittent rapamycin administration on glucose metabolism and immune system of SAMP8 and SAMR1 mice

Abstract: Aging involves a gradual decline in physiological integrity, and rapamycin (RAPA) has demonstrated potential as an anti-aging agent. Nonetheless, its effects on glucose…

Date: 2025-10-29

A murine model of prurigo nodularis-like skin lesions induced by persistent scratching under type 2 inflammatory conditions

Abstract: Prurigo nodularis (PN) is a chronic inflammatory dermatosis characterized by robust pruritus and highly keratinizing nodules sympathetically distributed on the trunk and…

Date: 2025-10-29

Single-cell RNA sequencing analysis reveals the critical role of fibroblasts in aortic progeria-associated vascular remodeling in Hutchinson-Gilford progeria syndrome mice

Abstract: Patients with Hutchinson-Gilford progeria syndrome (HGPS) typically succumb to cardiovascular diseases in their teens. Although fibroblasts have been implicated in the…

Date: 2025-10-29

Comparative real-world effectiveness and safety of biologics and JAK inhibitors in atopic dermatitis: short- and medium-to-long-term analysis from a regional healthcare network in southern Spain

Abstract: Biologics and Janus kinase (JAK) inhibitors have expanded treatment options for moderate-to-severe atopic dermatitis (AD), but comparative real-world data remain…

Date: 2025-10-29

Allergy diagnostic performance of FastCheckPOC 20 Atopy

Abstract: The increasing prevalence of allergic diseases, along with their diagnosis and treatment, presents a growing challenge in health care. To reduce this burden, a highly…

Date: 2025-10-29

Real-world safety profile of sonidegib: a disproportionality analysis based on the FDA adverse event reporting system

Abstract: Sonidegib is a novel treatment for locally advanced basal cell carcinoma (LaBCC) with demonstrated efficacy and safety in clinical trials. However, its real-world safety…

Date: 2025-10-29

Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice

Abstract: Atopic Dermatitis (AD), a chronic inflammatory skin disease characterized by pruritus, dryness, redness, edema, scratching, and lichenification, ranks as the leading…

Date: 2025-10-29

The clinical application of ear keloid using five-blade core excision combined with pressure and superficial electron beam radiation

Abstract: Surgical removal is the primary method for the clinical treatment of ear keloids. However, there are numerous surgical options available, and no standardized approach in…

Date: 2025-10-29

Lichen sclerosus and the association with subsequent psychiatric disorders

Abstract: Lichen sclerosus (LS) is an acquired, non-communicable, chronic inflammatory disease that predominantly affects the genital area and may lead to substantial impairment…

Date: 2025-10-29